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The Science Behind LED Light

How Does Light Affect The Human Body

For Surface-Level Skin Issues 

  • Bacterial Control: Targets Propionibacterium acnes, reducing acne-causing bacteria.
  • Sebum Regulation: Reduces sebaceous gland activity to manage excess oil production.
  • Enhanced Healing: Interact with hemoglobin to increase blood flow or even stimulate healing in the skin and underlying tissues.

Targeting the Epidermis and Upper Dermis Layers

  • Skin Repair & Anti-Aging: Stimulates fibroblasts to boost skin elasticity, reduce wrinkles, and improve texture.
  • Faster Tissue Regeneration: Boosts ATP production, promoting cell regeneration for faster tissue repair and recovery in superficial tissues.
  • Improved Circulation: Enhances blood flow in skin and tissues to support overall skin health and healing.
  • Inflammation Reduction: Stimulates anti-inflammatory cytokines to reduce swelling and ease discomfort in the skin.
  • Stimulates hair follicles: Encouraging hair growth and reducing hair loss, especially in cases of androgenic alopecia.

Targets deep Tissues, Muscles, Joints, and Internal Organs

  • Deep Tissue Penetration: penetrates muscles and joints, boosting mitochondrial ATP production to support deep tissue recovery.
  • Pain & Inflammation Relief: Promoting nitric oxide release, which dilates blood vessels and improves circulation in deeper tissues.
  • Tissue Repair & Regeneration: Boosts cell proliferation in deeper tissues, improving wound healing, scar repair, and muscle recovery at deeper levels than red light.
  • Stress Relief: Stimulates endorphin release, providing relief from chronic pain and muscle fatigue at deeper tissue levels.
  • Improved Circulation: Enhances blood flow to support deep tissue healing and recovery.

LED light therapy devices must be designed and built based on established scientific principles to ensure their effectiveness.

Devices that do not follow these principles are essentially ordinary light bulbs. No matter how it is debated, the following points are grounded in science, not opinions. They are based on scientific evidence and facts.

5 Scientific factors that differentiate Celluma

Proven Wavelengths

Wavelength is important because it determines whether it can penetrate the skin to interact with chromophores within cells. Chromophores, such as cytochrome c oxidase in mitochondria, have specific absorption ranges. These ranges correspond to precise wavelengths of light, which trigger biological processes when absorbed.


If the light’s wavelength does not align with the chromophore’s absorption range, the intended biochemical reaction will not occur. For example, cytochrome c oxidase absorbs red (around 660 nm) and near-infrared light (800-880 nm) to enhance ATP production. Using an unsuitable wavelength that falls out of this range would fail to activate this pathway, rendering the therapy ineffective.

What to look for:

  • For a product to be classified as a medical device and registered with regulatory authorities, it must meet stringent standards and demonstrate clinically verified therapeutic benefits. Choosing registered devices ensures you are selecting a solution with proven efficacy and safety. Be cautious of devices with unclear origins or companies making exaggerated marketing claims without substantiation.

Power Output

Many people mistakenly believe that measuring the intensity of light is the most reliable way to assess a light therapy device. However, intensity, measured as irradiance (mW/cm²), only only provides a snapshot of how strong the light is at that specific moment. It doesn’t give a complete picture of how much light your skin absorbs over the course of the session. 


Joules (J) is a more reliable way to measure light therapy because it takes into account the total amount of energy delivered to the skin over the entire treatment time. In simple terms, Joules measure how much "work" the light has done.

Manufacturers who emphasize irradiance (mW/cm²) in their product specifications want to create the illusion of a more powerful and effective device while omitting the crucial detail of how much energy is actually delivered to your skin. 


What to look for

A reliable manufacturer will specify the total energy delivered over the course of a treatment session, measured in Joules, rather than just focusing on irradiance (mW/cm²). This approach provides a more accurate understanding of the device’s effectiveness, as irradiance only measures the light's intensity at a specific point in time. Intensity alone doesn't reflect how the light interacts with your skin throughout the entire treatment period or the total energy that is absorbed. 

Delivery Distance

The primary reason for placing an LED device as close to the skin as possible is to prevent energy dissipation. As distance increases, light energy spreads over a larger area, reducing its intensity and biological impact.


According to the inverse square law, light intensity decreases in proportion to the square of the distance from its source. For example, doubling the distance reduces the intensity to just one-quarter. This dramatic drop in energy can significantly affect the therapy's effectiveness


While manufacturers may make various claims, the principles of energy dissipation and the inverse square law are established scientific facts. These laws govern the behavior of light and are not open to interpretation. It’s important to differentiate between these verified facts and marketing claims to ensure a clear and accurate understanding of how light therapy devices function.

Treatment Time

While quick treatments are appealing, LED therapy requires an optimal timeframe of 20 to 30 minutes to be effective because this allows the light energy to penetrate the skin and interact with the cells at a sufficient depth. During this time, the light is absorbed by chromophores (like cytochrome c oxidase in mitochondria), triggering biological processes such as increased ATP production, enhanced collagen synthesis, or reduced inflammation.


If the treatment time is too short, the cells may not absorb enough energy to stimulate these processes, while longer sessions may not provide additional benefits and can waste energy. The 20 to 30-minute window strikes a balance between sufficient energy absorption and effective therapeutic outcomes, based on clinical research and established treatment protocols.


What to look for:

Adequate treatment time ensures sufficient energy is delivered to achieve effective results without risking overexposure. Extremely short sessions, such as 5 minutes, typically indicate inadequate energy delivery.

Pulsing Mode

You may be wondering what is the pulse mode for if you are using a Celluma device or might have noticed Celluma's light pulsating like a disco ball during treatment! This rhythmic blinking isn’t just for show; it’s actually part of our carefully designed strategy that’s backed by science—and it’s one of the reasons Celluma continues to win prestigious awards year after year.


Renowned researcher Dr. Daniel Barolet has extensively studied the benefits of pulsing light in LED therapy. His research shows that pulsing enhances energy transfer to the cells, allowing for better absorption and promoting cellular communication. Pulsing light allows cells to recover between bursts of energy, which can help increase overall absorption and improve therapeutic outcomes like reducing inflammation, promoting healing, and enhancing ATP production in the mitochondria.


This dynamic approach not only optimizes the treatment’s effectiveness but also taps into the natural rhythms of our bodies, making it a powerful tool for skin rejuvenation and healing.


Science is the backbone of everything we do
. Every feature of our devices, from the flexible design to the carefully selected light wavelengths, is rooted in rigorous research and clinical trials. This evidence-based approach ensures that when you choose our products, you're getting solutions that deliver real, measurable results—backed by proven science.

What is Mitochondria and why is it important?

Mitochondria produces ATP (adenosine triphosphate) for our cells, the essential energy that drives vital cellular functions such as repair, growth, and overall health maintenance.
Nearly every cell in the body contains mitochondria, with their numbers varying based on the energy demands of each cell. 
Energy-intensive cells, like those in the muscles, heart, liver, and brain, contain significantly more mitochondria. For example, mitochondria make up approximately 40% of a heart muscle cell’s volume and 25% of a liver cell’s volume.
When mitochondria function at their best, they supply the energy needed for critical tasks, from muscle contraction, and fighting infection to tissue repair and regeneration.

How Light Helps Mitochondria Produce Energy More Efficiently?

光如何帮助线粒体更有效地产生能量?

点击了解优化的线粒体如何改变您的身体!

If you want real and effective results, try Celluma’s medical-grade LED Light Therapy device and see the difference yourself. 

Don’t take our word for it but regulatory bodies in 98 Countries can’t be wrong

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临床研究支持

过去 50 年来,数千项研究已通过临床证明,证明低强度 LED 光疗和红光疗法应用于人体后,产生越来越多的生物学效应和治疗益处。
  1. 有效低强度光疗 (LLLT) 的关键。 斯坦福医学院,2016 年
  2. 低强度激光(光)治疗的要点。PubMed ,2012 年
  3. 光生物调节抗炎作用的机制和应用。PubMed ,2017
  4. 低强度光疗中的双相剂量反应。PubMed ,2009 年。
  1. 使用发光二极管进行低强度光疗,治疗面部衰老。 整形外科诊所,2016 年
  2. 低强度激光(光)疗法 (LLLT) 用于美容医学和皮肤病学。Photobiology.info ,2014 年
  3. 皮肤病学中的发光二极管 (LED) 。PDF:Elsevier,2008 年
  4. 低强度激光(光)疗法(LLLT)在皮肤中的应用:刺激、愈合、恢复。PubMed ,2014 年
  1. 使用低强度光疗法塑造身体轮廓,2013 年。 完整 PDF | PubMed 摘要
  2. 低强度激光疗法减少脂肪层:综合评论。 《激光外科医学》,2014 年
  3. 回顾非侵入性塑身设备对脂肪团和皮下脂肪的作用机制和效果。PubMed ,2016 年
  4. 低强度激光疗法对身体塑形和局部脂肪减少的功效。PubMed ,2011 年
  1. 低强度光疗 (LLLT) 在雄激素性脱发中的作用。PubMed ,2021 年
  2. 光生物调节治疗脱发:作用机制、患者选择和观点。PubMed ,2019 年
  3. 低强度激光(光)疗法 (LLLT) 可治疗脱发。PubMed ,2014 年
  4. 使用可见红光激光和 LED 光源观察女性头皮毛发的生长情况。 美国国立卫生研究院,2014 年
  1. 低强度激光和 LED(光生物调节疗法)用于控制最常见的肌肉骨骼疾病的疼痛。PubMed ,2022 年
  2. 光生物调节抗炎作用的机制和应用。PubMed ,2017
  3. 使用低强度激光疗法 (LLLT) 治疗肌肉骨骼疼痛。PDF :MedCrave,2015 年
  4. 890 nm 光疗对慢性腰痛的短期治疗效果,2014 年。PubMed 摘要
  1. 蓝光对寻常痤疮的影响:系统评价。Sensors (Basel),2021 年
  2. 蓝光和红光联合 LED 光疗治疗 IV 型皮肤患者的寻常痤疮。Lasers Surg. Med.,2007
  3. 发光二极管在皮肤治疗中的应用:系统评价和荟萃分析。 光免疫学与光医学,2023 年

低强度光疗- 4 项研究

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皮肤老化- 4 项研究

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